They just approved the first drug that fixes the actual cause of narcolepsy. The most common side effect is insomnia. We didn't cure it. We overshot it. Send this to the sleep doc who has been waiting twenty years for this.

EXPLAINED (ACCURACY-CHECKED)

The FDA approved oveporexton (ORZEYFUL) on Aug 5, 2026 — the first oral orexin receptor 2 agonist — for narcolepsy type 1, targeting the underlying orexin signaling deficit. The most common adverse events in the pivotal trials were insomnia and urinary urgency/frequency.